Publikationen 2016

Darwiche K, Karpf-Wissel R, Eisenmann S, Aigner C, Welter S, Zarogoulidis P, Hohenforst-Schmidt W, Freitag L, Oezkan F. Bronchoscopic Lung Volume Reduction with Endobronchial Valves in Low-FEV1 Patients. Respiration. 2016 Nov 12;92(6). [Epub ahead of print] PubMed PMID: 27838695.


Wiesweg M, Eberhardt WE, Reis H, Ting S, Savvidou N, Skiba C, Herold T, Christoph DC, Meiler J, Worm K, Kasper S, Theegarten D, Hense J, Hager T, Darwiche K, Oezkan F, Aigner C, Welter S, Kühl H, Stuschke M, Schmid KW, Schuler M. High Prevalence of Concomitant Oncogene Mutations in Prospectively Identified Patients with ROS1-Positive Metastatic Lung Cancer. J Thorac Oncol. 2016 Aug 27. pii: S1556-0864(16)30904-2. doi: 10.1016/j.jtho.2016.08.137. [Epub ahead of print] PubMed PMID: 27575422.


Hoda MA, Dong Y, Rozsas A, Klikovits T, Laszlo V, Ghanim B, Stockhammer P, Ozsvar J, Jakopovic M, Samarzija M, Brcic L, Bendek M, Szirtes I, Reid G, Kirschner MB, Kao SC, Opitz I, Weder W, Frauenfelder T, Nguyen-Kim TD, Aigner C, Klepetko W, van Zandwijk N, Berger W, Dome B, Grusch M, Hegedus B. Circulating activin A is a novel prognostic biomarker in malignant pleural mesothelioma – A multi-institutional study. Eur J Cancer. 2016 Aug;63:64-73. doi: 10.1016/j.ejca.2016.04.018. PubMed PMID: 27288871.


Long X, He X, Ohshimo S, Griese M, Sarria R, Guzman J, Costabel U, Bonella F. Serum YKL-40 as predictor of outcome in hypersensitivity pneumonitis. Eur Respir J. 2016 Nov 11. pii: ERJ-01924-2015. doi: 10.1183/13993003.01924-2015. [Epub ahead of print] PubMed PMID: 27836954.


Kreuter M, Wijsenbeek MS, Vasakova M, Spagnolo P, Kolb M, Costabel U, Weycker D, Kirchgaessler KU, Maher TM. Unfavourable effects of medically indicated oral anticoagulants on survival in idiopathic pulmonary fibrosis: methodological concerns. Eur Respir J. 2016 Nov;48(5):1524-1526. doi: 10.1183/13993003.01482-2016. PubMed PMID: 27799399.


Kreuter M, Bonella F, Maher TM, Costabel U, Spagnolo P, Weycker D, Kirchgaessler KU, Kolb M. Effect of statins on disease-related outcomes in patients with idiopathic pulmonary fibrosis. Thorax. 2016 Oct 5. pii: thoraxjnl-2016-208819. doi: 10.1136/thoraxjnl-2016-208819. [Epub ahead of print]  PubMed PMID: 27708114.


Kreuter M, Birring SS, Wijsenbeek M, Wapenaar M, Oltmanns U, Costabel U, Bonella F. [German Validation of the „King’s Brief Interstitial Lung Disease (K-Bild) Health Status Questionnaire“]. Pneumologie. 2016 Nov;70(11):742-746. German. PubMed PMID: 27652583.


Kreuter M, Wuyts W, Renzoni E, Koschel D, Maher TM, Kolb M, Weycker D, Spagnolo P, Kirchgaessler KU, Herth FJ, Costabel U. Anti-acid treatment in patients with IPF: interpret results from post-hoc, subgroup, and exploratory analyses with great caution – Authors‘ reply. Lancet Respir Med. 2016 Sep;4(9):e48. doi: 10.1016/S2213-2600(16)30235-1. PubMed PMID: 27599251.


Campo I, Luisetti M, Griese M, Trapnell BC, Bonella F, Grutters J, Nakata K, Van Moorsel CH, Costabel U, Cottin V, Ichiwata T, Inoue Y, Braschi A, Bonizzoni G, Iotti GA, Tinelli C, Rodi G; WLL International Study Group.. Whole lung lavage therapy for pulmonary alveolar proteinosis: a global survey of current practices and procedures. Orphanet J Rare Dis. 2016 Aug 31;11(1):115. doi: 10.1186/s13023-016-0497-9. PubMed PMID: 27577926; PubMed Central PMCID: PMC5006612.


Baughman RP, Field S, Costabel U, Crystal RG, Culver DA, Drent M, Judson MA, Wolff G. Sarcoidosis in America. Analysis Based on Health Care Use. Ann Am Thorac Soc. 2016 Aug;13(8):1244-52. doi: 10.1513/AnnalsATS.201511-760OC. PubMed PMID: 27509154.


Albera C, Costabel U, Fagan EA, Glassberg MK, Gorina E, Lancaster L, Lederer DJ, Nathan SD, Spirig D, Swigris JJ. Efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis with more preserved lung function. Eur Respir J. 2016 Sep;48(3):843-51. doi: 10.1183/13993003.01966-2015. PubMed PMID: 27471208.


Costabel U, Wessendorf TE, Bonella F. [Epidemiology and Clinical Presentation of Sarcoidosis]. Klin Monbl Augenheilkd. 2016 Jul 25. [Epub ahead of print] German. PubMed PMID: 27454307.


Campo I, Luisetti M, Griese M, Trapnell BC, Bonella F, Grutters JC, Nakata K, Van Moorsel CH, Costabel U, Cottin V, Ichiwata T, Inoue Y, Braschi A, Bonizzoni G, Iotti GA, Tinelli C, Rodi G; WLL International Study Group.. A Global Survey on Whole Lung Lavage in Pulmonary Alveolar Proteinosis. Chest. 2016 Jul;150(1):251-3. doi: 10.1016/j.chest.2016.04.030. PubMed PMID: 27396783.


Bonella F, Long X, Ohshimo S, Horimasu Y, Griese M, Guzman J, Kohno N, Costabel U. MUC1 gene polymorphisms are associated with serum KL-6 levels and pulmonary dysfunction in pulmonary alveolar proteinosis. Orphanet J Rare Dis. 2016 Apr 23;11:48. doi: 10.1186/s13023-016-0430-2. PubMed PMID: 27108412; PubMed Central PMCID: PMC4841967.


Strek ME, Costabel U. Interstitial pneumonia with autoimmune features: a critical appraisal of the new definition. Curr Opin Pulm Med. 2016 Sep;22(5):442-9. doi: 10.1097/MCP.0000000000000298. PubMed PMID: 27379968.


Kreuter M, Wijsenbeek MS, Vasakova M, Spagnolo P, Kolb M, Costabel U, Weycker D, Kirchgaessler KU, Maher TM. Unfavourable effects of medically indicated oral anticoagulants on survival in idiopathic pulmonary fibrosis. Eur Respir J. 2016 Jun;47(6):1776-84. doi: 10.1183/13993003.02087-2015. Erratum in: Eur Respir J. 2016 Aug;48(2):593. PubMed PMID: 27103382.


Costabel U, Bonella F. How to handle IPF–the new Portuguese consensus document. Rev Port Pneumol (2006). 2016 Mar-Apr;22(2):70-2. doi: 10.1016/j.rppnen.2016.03.001. PubMed PMID: 27056483.


Boerner EB, Costabel U, Wessendorf TE, Theegarten D, Hetzel M, Drent M, Bonella F. Pulmonary alveolar proteinosis: another autoimmune disease associated  with sarcoidosis? Sarcoidosis Vasc Diffuse Lung Dis. 2016 Mar 29;33(1):90-4. PubMed PMID: 27055841.


Mölleken C, Poschmann G, Bonella F, Costabel U, Sitek B, Stühler K, Meyer HE, Schmiegel WH, Marcussen N, Helmer M, Nielsen O, Hansen S, Schlosser A, Holmskov U, Sorensen GL. MFAP4: a candidate biomarker for hepatic and pulmonary fibrosis? Sarcoidosis Vasc Diffuse Lung Dis. 2016 Mar 29;33(1):41-50. PubMed PMID: 27055835.


Kreuter M, Wuyts W, Renzoni E, Koschel D, Maher TM, Kolb M, Weycker D, Spagnolo P, Kirchgaessler KU, Herth FJ, Costabel U. Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis. Lancet Respir Med. 2016 May;4(5):381-9. doi: 10.1016/S2213-2600(16)00067-9. PubMed PMID: 27050871.


Nathan SD, Albera C, Bradford WZ, Costabel U, du Bois RM, Fagan EA, Fishman RS, Glaspole I, Glassberg MK, Glasscock KF, King TE Jr, Lancaster L, Lederer DJ, Lin Z, Pereira CA, Swigris JJ, Valeyre D, Noble PW, Wells AU. Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with idiopathic pulmonary fibrosis. Thorax. 2016 May;71(5):429-35. doi: 10.1136/thoraxjnl-2015-207011. PubMed PMID: 26968970; PubMed Central PMCID: PMC4862066.


Knoch CJ, Costabel U, Wessendorf T. [58-year old woman with primary biliary cirrhosis and crepitations]. Dtsch Med Wochenschr. 2016 Feb;141(4):241. doi: 10.1055/s-0042-100629. German. PubMed PMID: 26886033.


Baughman RP, Judson MA, Lower EE, Drent M, Costabel U, Flavin S, Lo KH, Barnathan ES; Sarcoidosis Investigators.. Infliximab for chronic cutaneous sarcoidosis: a subset analysis from a double-blind randomized clinical trial. Sarcoidosis Vasc Diffuse Lung Dis. 2016 Jan 15;32(4):289-95. PubMed PMID: 26847095.


Lancaster L, Albera C, Bradford WZ, Costabel U, du Bois RM, Fagan EA, Fishman RS, Glaspole I, Glassberg MK, King TE Jr, Lederer DJ, Lin Z, Nathan SD, Pereira CA, Swigris JJ, Valeyre D, Noble PW. Safety of pirfenidone in patients with idiopathic pulmonary fibrosis: integrated analysis of cumulative data from 5 clinical trials. BMJ Open Respir Res. 2016 Jan 12;3(1):e000105. doi: 10.1136/bmjresp-2015-000105. PubMed PMID: 26835133; PubMed Central PMCID: PMC4716177.


Wuyts WA, Bonella F, Costabel U, Cottin V, Kreuter M, Poletti V, Spagnolo P. An Important Step Forward, but Still a Way to Go. Am J Respir Crit Care Med. 2016 Feb 1;193(3):340-1. doi: 10.1164/rccm.201509-1763LE. PubMed PMID: 26829426.


Scheidl SJ, Kusej M, Flick H, Stacher E, Matzi V, Kovacs G, Popper HH, Costabel U, Olschewski H. Clinical Manifestations of Respiratory Bronchiolitis as an Incidental Finding in Surgical Lung Biopsies: A Retrospective Analysis of a Large Austrian Registry. Respiration. 2016;91(1):26-33. doi: 10.1159/000442053. PubMed PMID: 26656753.


Noble PW, Albera C, Bradford WZ, Costabel U, du Bois RM, Fagan EA, Fishman RS, Glaspole I, Glassberg MK, Lancaster L, Lederer DJ, Leff JA, Nathan SD, Pereira CA, Swigris JJ, Valeyre D, King TE Jr. Pirfenidone for idiopathic pulmonary fibrosis: analysis of pooled data from three multinational phase 3 trials. Eur Respir J. 2016 Jan;47(1):243-53. doi: 10.1183/13993003.00026-2015. PubMed PMID: 26647432.


Tomassetti S, Wells AU, Costabel U, Cavazza A, Colby TV, Rossi G, Sverzellati N, Carloni A, Carretta E, Buccioli M, Tantalocco P, Ravaglia C, Gurioli C, Dubini A, Piciucchi S, Ryu JH, Poletti V. Bronchoscopic Lung Cryobiopsy Increases Diagnostic Confidence in the Multidisciplinary Diagnosis of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2016 Apr 1;193(7):745-52. doi: 10.1164/rccm.201504-0711OC. PubMed PMID: 26562389.


Costabel U, Inoue Y, Richeldi L, Collard HR, Tschoepe I, Stowasser S, Azuma A. Efficacy of Nintedanib in Idiopathic Pulmonary Fibrosis across Prespecified Subgroups in INPULSIS. Am J Respir Crit Care Med. 2016 Jan 15;193(2):178-85. doi: 10.1164/rccm.201503-0562OC. PubMed PMID: 26393389.


Valipour A, Slebos DJ, Herth F, Darwiche K, Wagner M, Ficker JH, Petermann C,  Hubner RH, Stanzel F, Eberhardt R; IMPACT Study Team. Endobronchial Valve Therapy in Patients with Homogeneous Emphysema. Results from the IMPACT Study. Am J Respir Crit Care Med. 2016 Nov 1;194(9):1073-1082. PubMed PMID: 27580428.


Kampe S, Rocha M, Darwiche K, Ebmeyer U, Georgios S. [Sufficient high frequency jet ventilation during a period of 2.5 h – Airway management during resection of a tracheaesophageal fistula and tracheal resection]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2016 Jun;51(6):368-71. doi: 10.1055/s-0041-110265. German. PubMed PMID: 27359233.


Pöttgen C, Gauler T, Bellendorf A, Guberina M, Bockisch A, Schwenzer N, Heinzelmann F, Cordes S, Schuler MH, Welter S, Stamatis G, Friedel G, Darwiche K, Jöckel KH, Eberhardt W, Stuschke M. Standardized Uptake Decrease on [18F]-Fluorodeoxyglucose Positron Emission Tomography After Neoadjuvant Chemotherapy Is a Prognostic Classifier for Long-Term Outcome After Multimodality Treatment: Secondary Analysis of a Randomized Trial for Resectable Stage IIIA/B Non-Small-Cell Lung Cancer. J Clin Oncol. 2016 Jul 20;34(21):2526-33. doi: 10.1200/JCO.2015.65.5167. PubMed PMID: 27247220.


Stang A, Kowall B, Schuler M, Darwiche K, Kühl H, Jöckel KH. In Reply. Dtsch Arztebl Int. 2016 Apr 29;113(17):297-8. doi: 10.3238/arztebl.2016.0297b. PubMed PMID: 27173409; PubMed Central PMCID: PMC4873674.


Hohenforst-Schmidt W, Zarogoulidis P, Steinheimer M, Benhassen N, Tsiouda T, Baka S, Yarmus L, Stratakos G, Organtzis J, Pataka A, Tsakiridis K, Karapantzos I, Karapantzou C, Darwiche K, Zissimopoulos A, Pitsiou G, Zarogoulidis K, Man YG, Rittger H. Tyrosine Kinase Inhibitors for the Elderly. J Cancer. 2016 Mar 21;7(6):687-93. doi: 10.7150/jca.14819. Review. PubMed PMID: 27076850; PubMed Central PMCID: PMC4829555.


Zaric B, Stojsic V, Carapic V, Kovacevic T, Stojanovic G, Panjkovic M, Kioumis I, Darwiche K, Zarogoulidis K, Stratakos G, Tsavlis D, Hohenforst-Schmidt W, Pitsiou G, Zissimopoulos A, Sachpekidis N, Karapantzos I, Karapantzou C, Zarogoulidis P, Perin B. Radial Endobronchial Ultrasound (EBUS) Guided Suction Catheter-Biopsy in Histological Diagnosis of Peripheral Pulmonary Lesions. J Cancer. 2016 Jan 1;7(1):7-13. doi: 10.7150/jca.13081. PubMed PMID: 26722354; PubMed Central PMCID: PMC4679375.


Köhler J, Schuler M, Gauler TC, Nöpel-Dünnebacke S, Ahrens M, Hoffmann AC, Kasper S, Nensa F, Gomez B, Hahnemann M, Breitenbuecher F, Cheufou D, Özkan F, Darwiche K, Hoiczyk M, Reis H, Welter S, Eberhardt WE, Eisenacher M, Teschler H,  Stamatis G, Schmiegel W, Hahn SA, Baraniskin A. Circulating U2 small nuclear RNA  fragments as a diagnostic and prognostic biomarker in lung cancer patients. J Cancer Res Clin Oncol. 2016 Apr;142(4):795-805. doi: 10.1007/s00432-015-2095-y. PubMed PMID: 26687686.


Welter S, Cheufou D, Zahin M, Kampe S, Darwiche K, Weinreich G, Stamatis G. Short- and Mid-Term Changes in Lung Function after Bilateral Pulmonary Metastasectomy. Thorac Cardiovasc Surg. 2016 Mar;64(2):139-45. doi: 10.1055/s-0034-1383828. PubMed PMID: 25068776.


Zarogoulidis P, Petanidis S, Domvri K, Kioseoglou E, Anestakis D, Freitag L, Zarogoulidis K, Hohenforst-Schmidt W, Eberhardt W. Autophagy inhibition upregulates CD4(+) tumor infiltrating lymphocyte expression via miR-155 regulation and TRAIL activation. Mol Oncol. 2016 Sep 16. pii: S1574-7891(16)30086-2. doi: 10.1016/j.molonc.2016.08.005. [Epub ahead of print] PubMed PMID: 27692344.


Eberhardt W, Badawi A, Biyanee A, Pfeilschifter J. Cytoskeleton-Dependent Transport as a Potential Target for Interfering with Post-transcriptional HuR mRNA Regulons. Front Pharmacol. 2016 Aug 17;7:251. doi: 10.3389/fphar.2016.00251. Review. PubMed PMID: 27582706; PubMed Central PMCID: PMC4987335.


Schuette W, Dietel M, Thomas M, Eberhardt W, Griesinger F, Zirrgiebel U, Radke S, Schirmacher P. [Exon-dependent Subgroup-analysis of the Non-interventional REASON-Study: PFS and OS in EGFR-mutated NSCLC Patients Treated with Gefitinib or Chemotherapy]. Pneumologie. 2016 Aug;70(8):514-21. doi: 10.1055/s-0042-109749. German. PubMed PMID: 27512931.


Joerger M, von Pawel J, Kraff S, Fischer JR, Eberhardt W, Gauler TC, Mueller L, Reinmuth N, Reck M, Kimmich M, Mayer F, Kopp HG, Behringer DM, Ko YD, Hilger RA, Roessler M, Kloft C, Henrich A, Moritz B, Miller MC, Salamone SJ, Jaehde U. Open-label, randomized study of individualized, pharmacokinetically (PK)-guided dosing of paclitaxel combined with carboplatin or cisplatin in patients with advanced non-small-cell lung cancer (NSCLC). Ann Oncol. 2016 Oct;27(10):1895-902. doi: 10.1093/annonc/mdw290. PubMed PMID: 27502710.


Pan Q, Freitag L, Kowacs T, Falgenhauer JC, Korterik JP, Schlettwein D, Browne WR, Pryce MT, Rau S, González L, Vos JG, Huijser A. Peripheral ligands as electron storage reservoirs and their role in enhancement of photocatalytic hydrogen generation. Chem Commun (Camb). 2016 Aug 4;52(60):9371-4. doi: 10.1039/c6cc05222c. PubMed PMID: 27367442.


Franzen D, Bratton DJ, Clarenbach CF, Freitag L, Kohler M. Target-controlled versus fractionated propofol sedation in flexible bronchoscopy: A randomized noninferiority trial. Respirology. 2016 Nov;21(8):1445-1451. doi: 10.1111/resp.12830. PubMed PMID: 27302000.


Franzen D, Diacon AH, Freitag L, Schubert PT, Wright CA, Schuurmans MM. Ultrathin bronchoscopy for solitary pulmonary lesions in a region endemic for tuberculosis: a randomised pilot trial. BMC Pulm Med. 2016 Apr 27;16(1):62. doi:  10.1186/s12890-016-0225-1. PubMed PMID: 27117455; PubMed Central PMCID: PMC4847358.


Hohenforst-Schmidt W, Zarogoulidis P, Pitsiou G, Linsmeier B, Tsavlis D, Kioumis I, Papadaki E, Freitag L, Tsiouda T, Turner JF, Browning R, Simoff M, Sachpekidis N, Tsakiridis K, Zaric B, Yarmus L, Baka S, Stratakos G, Rittger H. Drug Eluting Stents for Malignant Airway Obstruction: A Critical Review of the Literature. J Cancer. 2016 Jan 13;7(4):377-90. doi: 10.7150/jca.13611. Review. PubMed PMID: 26918052; PubMed Central PMCID: PMC4749359.


Bezel P, Tischler V, Robinson C, Baumueller S, Bode-Lesniewska B, Kohler M, Freitag L, Franzen D. Diagnostic Value of Bronchoalveolar Lavage for Diagnosis of Suspected Peripheral Lung Cancer. Clin Lung Cancer. 2016 Sep;17(5):e151-e156. doi: 10.1016/j.cllc.2015.12.012. PubMed PMID: 26831835. Oezkan F, Khan AM, Hager T, Freitag L, Christoph D, Darwiche K. OSNA: A Fast Molecular Test Based on CK19 mRNA Concentration for Assessment of EBUS-TBNA Samples in Lung Cancer Patients. Clin Lung Cancer. 2016 May;17(3):198-204. doi: 10.1016/j.cllc.2015.09.001. PubMed PMID: 26455862.


Kampe S, Geismann B, Weinreich G, Stamatis G, Ebmeyer U, Gerbershagen HJ. The  Influence of Type of Anesthesia, Perioperative Pain, and Preoperative Health Status on Chronic Pain Six Months After Thoracotomy-A Prospective Cohort Study. Pain Med. 2016 Sep 20. pii: pnw230. [Epub ahead of print] PubMed PMID: 27651509.


Roesel C, Terjung S, Weinreich G, Gauler T, Theegarten D, Stamatis G, Welter S. A Single-Institution Analysis of the Surgical Management of Pulmonary Large Cell Neuroendocrine Carcinomas. Ann Thorac Surg. 2016 May;101(5):1909-14. doi: 10.1016/j.athoracsur.2015.12.009. PubMed PMID: 26897321.


Kreuter M, Vansteenkiste J, Fischer JR, Eberhardt WE, Zabeck H, Kollmeier J, Serke M, Frickhofen N, Reck M, Engel-Riedel W, Neumann S, Thomeer M, Schumann C,  De Leyn P, Graeter T, Stamatis G, Griesinger F, Thomas M; TREAT investigators. Three-Year Follow-Up of a Randomized Phase II Trial on Refinement of Early-Stage NSCLC Adjuvant Chemotherapy with Cisplatin and Pemetrexed versus Cisplatin and Vinorelbine (the TREAT Study). J Thorac Oncol. 2016 Jan;11(1):85-93. doi: 10.1016/j.jtho.2015.09.014. PubMed PMID: 26762743.


von Leupoldt A, Reijnders T, Schuler M, Wittmann M, Jelusic D, Schultz K. Validity of a Self-administered Questionnaire Version of the Transition Dyspnea Index in Patients with COPD. COPD. 2016 Nov 14:1-6. [Epub ahead of print] PubMed PMID: 27841688.


da Costa PL, Melo VN, Guimarães BM, Schuler M, Pimenta V, Rollin P, Tatibouët A, de Oliveira RN. Glycerol carbonate in Ferrier reaction: Access to new enantiopure building blocks to develop glycoglycerolipid analogues. Carbohydr Res. 2016 Oct 26;436:1-10. doi: 10.1016/j.carres.2016.10.009. [Epub ahead of print] PubMed PMID: 27816891.


Yang JC, Sequist LV, Zhou C, Schuler M, Geater SL, Mok T, Hu CP, Yamamoto N, Feng J, O’Byrne K, Lu S, Hirsh V, Huang Y, Sebastian M, Okamoto I, Dickgreber N, Shah R, Märten A, Massey D, Wind S, Wu YL. Effect of dose adjustment on the safety and efficacy of afatinib for EGFR mutation-positive lung adenocarcinoma: post hoc analyses of the randomized LUX-Lung 3 and 6 trials. Ann Oncol. 2016 Nov;27(11):2103-2110. PubMed PMID: 27601237.


Al-Batran SE, Hofheinz RD, Pauligk C, Kopp HG, Haag GM, Luley KB, Meiler J, Homann N, Lorenzen S, Schmalenberg H, Probst S, Koenigsmann M, Egger M, Prasnikar N, Caca K, Trojan J, Martens UM, Block A, Fischbach W, Mahlberg R, Clemens M, Illerhaus G, Zirlik K, Behringer DM, Schmiegel W, Pohl M, Heike M, Ronellenfitsch U, Schuler M, Bechstein WO, Königsrainer A, Gaiser T, Schirmacher P, Hozaeel W, Reichart A, Goetze TO, Sievert M, Jäger E, Mönig S, Tannapfel A. Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomised phase 2/3 trial. Lancet Oncol. 2016 Oct 21. pii: S1470-2045(16)30531-9. doi: 10.1016/S1470-2045(16)30531-9. [Epub ahead of print] PubMed PMID: 27776843.


Fein L, Wu YL, Sequist LV, Geater SL, Orlov S, Lee KH, Tsai CM, Kato T, Kiura K, Barrios CH, Schuler M, Hirsh V, Yamamoto N, O’Byrne K, Mok T, Massey D, Märten A, Chih-Hsin Yang J. P1.33: Afatinib Versus Chemotherapy for EGFR Mutation-Positive NSCLC Patients Aged ≥65 Years: Subgroup Analysis of LUX-Lung 3/6: Track: Advanced NSCLC. J Thorac Oncol. 2016 Oct;11(10S):S202-S203. doi: 10.1016/j.jtho.2016.08.055. PubMed PMID: 27676519.


Barrios CH, Wu YL, Chih-Hsin Yang J, Sequist LV, Geater SL, Mok T, Hu CP, Yamamoto N, O’Byrne K, Lu S, Hirsh V, Sebastian M, Okamoto I, Shah R, Märten A, Massey D, Wind S, Schuler M. P1.45: Impact of Dose Adjustment on Afatinib Safety and Efficacy in EGFR Mutation-Positive NSCLC: Post-Hoc Analyses of LUX-Lung 3/6: Track: Advanced NSCLC. J Thorac Oncol. 2016 Oct;11(10S):S210-S211. doi: 10.1016/j.jtho.2016.08.067. PubMed PMID: 27676531.


Alma H, de Jong C, Jelusic D, Wittmann M, Schuler M, Blok BF, Kocks J,m Schultz K, Molen Tv. Health status instruments for patients with COPD in pulmonary rehabilitation: defining a minimal clinically important difference. NPJ Prim Care Respir Med. 2016 Sep 1;26:16041. doi: 10.1038/npjpcrm.2016.41. PubMed PMID: 27597571; PubMed Central PMCID: PMC5011855.


Ballard ST, Evans JW, Drag HS, Schuler M. PATHOPHYSIOLOGIC EVALUATION OF THE TRANSGENIC CFTR „GUT-CORRECTED“ PORCINE MODEL OF CYSTIC FIBROSIS. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 19:ajplung.00242.2016. doi: 10.1152/ajplung.00242.2016. [Epub ahead of print] PubMed PMID: 27542808.


Neuderth S, Schwarz B, Gerlich C, Schuler M, Markus M, Bethge M. Work-related medical rehabilitation in patients with musculoskeletal disorders: the protocol of a propensity score matched effectiveness study (EVA-WMR, DRKS00009780). BMC Public Health. 2016 Aug 17;16:804. doi: 10.1186/s12889-016-3437-7. PubMed PMID: 27534527; PubMed Central PMCID: PMC4989326.


Eulenburg C, Wegscheider K, Woehrle H, Angermann C, d’Ortho MP, Erdmann E, Levy P, Simonds AK, Somers VK, Zannad F, Teschler H, Cowie MR. Mechanisms underlying increased mortality risk in patients with heart failure and reduced ejection fraction randomly assigned to adaptive servoventilation in the SERVE-HF study: results of a secondary multistate modelling analysis. Lancet Respir Med. 2016 Nov;4(11):873-881. doi: 10.1016/S2213-2600(16)30244-2. PubMed PMID: 27592224.


Fassbender P, Herbstreit F, Eikermann M, Teschler H, Peters J. Obstructive Sleep Apnea-a Perioperative Risk Factor. Dtsch Arztebl Int. 2016 Jul 11;113(27-28):463-9. doi: 10.3238/arztebl.2016.0463. PubMed PMID: 27476705; PubMed Central PMCID: PMC4973000.


Sommerwerck U, Kleibrink BE, Kruse F, Scherer MJ, Wang Y, Kamler M, Teschler H, Weinreich G. Predictors of obstructive sleep apnea in lung transplant recipients. Sleep Med. 2016 May;21:121-5. doi: 10.1016/j.sleep.2016.01.005. PubMed PMID: 27448482.


Scherer MJ, Weinreich G, Kleibrink BE, Rabis T, Kamler M, Teschler H, Sommerwerck U. Decreased Hypercapnic Ventilatory Response in Long-Term Lung Transplant Recipients is Associated with Exercise Impairment. Lung. 2016 Aug;194(4):563-9. doi: 10.1007/s00408-016-9889-9. PubMed PMID: 27147224.


Cowie MR, Wegscheider K, Teschler H. Adaptive Servo-Ventilation for Central Sleep Apnea in Heart Failure. N Engl J Med. 2016 Feb 18;374(7):690-1. doi: 10.1056/NEJMc1515007. PubMed PMID: 26886528.


Arzt M, Woehrle H, Oldenburg O, Graml A, Suling A, Erdmann E, Teschler H, Wegscheider K; SchlaHF Investigators. Prevalence and Predictors of Sleep-Disordered Breathing in Patients With Stable Chronic Heart Failure: The SchlaHF Registry. JACC Heart Fail. 2016 Feb;4(2):116-25. doi: 10.1016/j.jchf.2015.09.014. PubMed PMID: 26682790.


Publikationen 2015 und 2014

Tomassetti S, Wells AU, Costabel U, Cavazza A, Colby TV, Rossi G, Sverzellati N, Carloni A, Carretta E, Buccioli M, Tantalocco P, Ravaglia C, Gurioli C, Dubini A, Piciucchi S, Ryu JH, Poletti V. Bronchoscopic Lung Cryobiopsy Increases Diagnostic Confidence in the Multidisciplinary Diagnosis of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2015 Nov 12. [Epub ahead of print] PubMed PMID: 26562389.


Eberhardt WE, Mitchell A, Crowley J, Kondo H, Kim YT, Turrisi A 3rd, Goldstraw P, Rami-Porta R. International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee, Advisory Board Members, and Participating Institutions. The IASLC Lung Cancer Staging Project: Proposals for the Revision of the M Descriptors in the Forthcoming Eighth Edition of the TNM Classification of Lung Cancer. J Thorac Oncol. 2015 Nov;10(11):1515-22. doi: 10.1097/JTO.0000000000000673. PubMed PMID: 26536193.


Eberhardt WE, Pöttgen C, Gauler TC, Friedel G, Veit S, Heinrich V, Welter S, Budach W, Spengler W, Kimmich M, Fischer B, Schmidberger H, De Ruysscher D, Belka C, Cordes S, Hepp R, Lütke-Brintrup D, Lehmann N, Schuler M, Jöckel KH, Stamatis G, Stuschke M. Phase III Study of Surgery Versus Definitive Concurrent Chemoradiotherapy Boost in Patients With Resectable Stage IIIA(N2) and Selected IIIB Non-Small-Cell Lung Cancer After Induction Chemotherapy and Concurrent Chemoradiotherapy (ESPATUE). J Clin Oncol. 2015 Nov 2. pii: JCO.2015.62.6812. [Epub ahead of print] PubMed PMID: 26527789.


Milovancev A, Stojsic V, Zaric B, Kovacevic T, Sarcev T, Perin B, Zarogoulidis K, Tsirgogianni K, Freitag L, Darwiche K, Tsavlis D, Zissimopoulos A, Stratakos G, Zarogoulidis P. EGFR-TKIs in adjuvant treatment of lung cancer: to give or not to give? Onco Targets Ther. 2015 Oct 13;8:2915-21. doi: 10.2147/OTT.S91627. eCollection 2015. Review. PubMed PMID: 26508876; PubMed Central PMCID: PMC4610780.


Raghu G, Martinez FJ, Brown KK, Costabel U, Cottin V, Wells AU, Lancaster L, Gibson KF, Haddad T, Agarwal P, Mack M, Dasgupta B, Nnane IP, Flavin SK, Barnathan ES. CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab. Eur Respir J. 2015 Oct 22. pii: ERJ-01558-2014. doi: 10.1183/13993003.01558-2014. [Epub ahead of print] PubMed PMID: 26493793.


Oezkan F, Khan AM, Hager T, Freitag L, Christoph D, Darwiche K. OSNA: A Fast Molecular Test Based on CK19 mRNA Concentration for Assessment of EBUS-TBNA Samples in Lung Cancer Patients. Clin Lung Cancer. 2015 Sep 21. pii: S1525-7304(15)00219-3. doi: 10.1016/j.cllc.2015.09.001. [Epub ahead of print] PubMed PMID: 26455862.


Stang A, Schuler M, Kowall B, Darwiche K, Kühl H, Jöckel KH. Lung Cancer Screening Using Low Dose CT Scanning in Germany. Dtsch Arztebl Int. 2015 Sep 18;112(38):637-44. doi: 10.3238/arztebl.2015.0637. PubMed PMID: 26429636; PubMed Central PMCID: PMC4593930.


Costabel U, Inoue Y, Richeldi L, Collard HR, Tschoepe I, Stowasser S, Azuma A. Efficacy of Nintedanib in Idiopathic Pulmonary Fibrosis Across Pre-specified Subgroups in INPULSIS®. Am J Respir Crit Care Med. 2015 Sep 22. [Epub ahead of print] PubMed PMID: 26393389.


Schuurmans MM, Palheiros Marques M, Freitag L, Zinkernagel AS, Achermann Y. Biofilm Formation in a Permanent Tracheal Stent Implanted for Twenty-Five Years. Respiration. 2015 Oct;90(4):327-8. doi: 10.1159/000439312. Epub 2015 Sep 10. PubMed PMID: 26351844.


Richly H, Kim TM, Schuler M, Kim DW, Harrison SJ, Shaw AT, Boral AL, Yovine A, Solomon B. Ceritinib in patients with advanced anaplastic lymphoma kinase-rearranged anaplastic large-cell lymphoma. Blood. 2015 Sep 3;126(10):1257-8. doi: 10.1182/blood-2014-12-617779. PubMed PMID: 26337354; PubMed Central PMCID: PMC4559938.


Kelly K, Altorki NK, Eberhardt WE, O’Brien ME, Spigel DR, Crinò L, Tsai CM, Kim JH, Cho EK, Hoffman PC, Orlov SV, Serwatowski P, Wang J, Foley MA, Horan JD, Shepherd FA. Adjuvant Erlotinib Versus Placebo in Patients With Stage IB-IIIA Non-Small-Cell Lung Cancer (RADIANT): A Randomized, Double-Blind, Phase III Trial. J Clin Oncol. 2015 Aug 31. pii: JCO.2015.61.8918. [Epub ahead of print] PubMed PMID: 26324372.


12: Cowie MR, Woehrle H, Wegscheider K, Angermann C, d’Ortho MP, Erdmann E, Levy P, Simonds AK, Somers VK, Zannad F, Teschler H. Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure. N Engl J Med. 2015 Sep 17;373(12):1095-105. doi: 10.1056/NEJMoa1506459. Epub 2015 Sep 1. PubMed PMID: 26323938.


Spagnolo P, Rossi G, Cavazza A, Bonifazi M, Paladini I, Bonella F, Sverzellati N, Costabel U. Hypersensitivity Pneumonitis: A Comprehensive Review. J Investig Allergol Clin Immunol. 2015;25(4):237-50; quiz follow 250. Review. PubMed PMID: 26310038.


Hyman DM, Puzanov I, Subbiah V, Faris JE, Chau I, Blay JY, Wolf J, Raje NS, Diamond EL, Hollebecque A, Gervais R, Elez-Fernandez ME, Italiano A, Hofheinz RD, Hidalgo M, Chan E, Schuler M, Lasserre SF, Makrutzki M, Sirzen F, Veronese ML, Tabernero J, Baselga J. Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations. N Engl J Med. 2015 Aug 20;373(8):726-36. doi: 10.1056/NEJMoa1502309. PubMed PMID: 26287849.


Eberhardt WE, Stuschke M. Multimodal treatment of non-small-cell lung cancer. Lancet. 2015 Sep 12;386(9998):1018-20. doi: 10.1016/S0140-6736(15)61083-2. Epub 2015 Aug 11. PubMed PMID: 26275734.


Griese M, Zarbock R, Costabel U, Hildebrandt J, Theegarten D, Albert M, Thiel A, Schams A, Lange J, Krenke K, Wesselak T, Schön C, Kappler M, Blum H, Krebs S, Jung A, Kröner C, Klein C, Campo I, Luisetti M, Bonella F. GATA2 deficiency in children and adults with severe pulmonary alveolar proteinosis and hematologic disorders. BMC Pulm Med. 2015 Aug 12;15:87. doi: 10.1186/s12890-015-0083-2. PubMed PMID: 26264606; PubMed Central PMCID: PMC4542098.


Wells AU, Costabel U, Poletti V, Crestani B, Egan J, Margaritopoulos G, Antoniou K. Challenges in IPF diagnosis, current management and future perspectives. Sarcoidosis Vasc Diffuse Lung Dis. 2015 Aug 3;32(1 Suppl):28-35. PubMed PMID: 26237442.


Behr J, Bonella F, Bonnet R, Gläser S, Grohé C, Günther A, Koschel D, Kreuter M, Kirsten D, Krögel C, Markart P, Müller-Quernheim J, Neurohr C, Pfeifer M, Prasse A, Schönfeld N, Schreiber J, Wirtz H, Witt C, Costabel U. [Position Paper: Significance of the Forced Vital Capacity in Idiopathic Pulmonary Fibrosis]. Pneumologie. 2015 Aug;69(8):455-8. doi: 10.1055/s-0034-1392602. Epub 2015 Jul 30. German. PubMed PMID: 26227628.


Gautschi O, Milia J, Cabarrou B, Bluthgen MV, Besse B, Smit EF, Wolf J, Peters S, Früh M, Koeberle D, Oulkhouir Y, Schuler M, Curioni-Fontecedro A, Huret B, Kerjouan M, Michels S, Pall G, Rothschild S, Schmid-Bindert G, Scheffler M, Veillon R, Wannesson L, Diebold J, Zalcman G, Filleron T, Mazières J. Targeted. Therapy for Patients with BRAF-Mutant Lung Cancer: Results from the European EURAF Cohort. J Thorac Oncol. 2015 Oct;10(10):1451-7. doi: 10.1097/JTO.0000000000000625. PubMed PMID: 26200454.


George J, Lim JS, Jang SJ, Cun Y, Ozretić L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco G, Müller C, Dahmen I, Jahchan NS, Park KS, Yang D, Karnezis AN, Vaka D, Torres A, Wang MS, Korbel JO, Menon R, Chun SM, Kim D, Wilkerson M, Hayes N, Engelmann D, Pützer B, Bos M, Michels S, Vlasic I, Seidel D, Pinther B, Schaub P, Becker C, Altmüller J, Yokota J, Kohno T, Iwakawa R, Tsuta K, Noguchi M, Muley T, Hoffmann H, Schnabel PA, Petersen I, Chen Y, Soltermann A, Tischler V, Choi CM, Kim YH, Massion PP, Zou Y, Jovanovic D, Kontic M, Wright GM, Russell PA, Solomon B, Koch I, Lindner M, Muscarella LA, la Torre A, Field JK, Jakopovic M, Knezevic J, Castaños-Vélez E, Roz L, Pastorino U, Brustugun OT, Lund-Iversen M, Thunnissen E, Köhler J, Schuler M, Botling J, Sandelin M, Sanchez-Cespedes M, Salvesen HB, Achter V, Lang U, Bogus M, Schneider PM, Zander T, Ansén S, Hallek M, Wolf J, Vingron M, Yatabe Y, Travis WD, Nürnberg P, Reinhardt C, Perner S, Heukamp L, Büttner R, Haas SA, Brambilla E, Peifer M, Sage J, Thomas RK. Comprehensive genomic profiles of small cell lung cancer. Nature. 2015 Aug 6;524(7563):47-53. doi: 10.1038/nature14664. Epub 2015 Jul 13. PubMed PMID: 26168399.


Weinreich G, Wessendorf TE, Pundt N, Weinmayr G, Hennig F, Moebus S, Möhlenkamp S, Erbel R, Jöckel KH, Teschler H, Hoffmann B; Heinz Nixdorf. Recall study group. Association of short-term ozone and temperature with sleep disordered breathing. Eur Respir J. 2015 Nov;46(5):1361-9. doi: 10.1183/13993003.02255-2014. Epub 2015 Jul 9. PubMed PMID: 26160864.


Rami-Porta R, Bolejack V, Crowley J, Ball D, Kim J, Lyons G, Rice T, Suzuki K, Thomas CF Jr, Travis WD, Wu YL. IASLC Staging and Prognostic Factors Committee, Advisory Boards and Participating Institutions. The IASLC Lung Cancer Staging Project: Proposals for the Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer. J Thorac Oncol. 2015 Jul;10(7):990-1003. doi: 10.1097/JTO.0000000000000559. PubMed PMID: 26134221.


Gore ME, Szczylik C, Porta C, Bracarda S, Bjarnason GA, Oudard S, Lee SH, Haanen J, Castellano D, Vrdoljak E, Schöffski P, Mainwaring P, Hawkins RE, Crinò L, Kim TM, Carteni G, Eberhardt WE, Zhang K, Fly K, Matczak E, Lechuga MJ, Hariharan S, Bukowski R. Final results from the large sunitinib global expanded-access trial in metastatic renal cell carcinoma. Br J Cancer. 2015 Jun 30;113(1):12-9. doi: 10.1038/bjc.2015.196. Epub 2015 Jun 18. PubMed PMID: 26086878.


Schuette W, Schirmacher P, Eberhardt WE, Fischer JR, von der Schulenburg JM, Mezger J, Schumann C, Serke M, Zaun S, Dietel M, Thomas M. EGFR mutation status and first-line treatment in patients with stage III/IV non-small cell lung cancer in Germany: an observational study. Cancer Epidemiol Biomarkers Prev. 2015 Aug;24(8):1254-61. doi: 10.1158/1055-9965.EPI-14-1149. Epub 2015 Jun 12. PubMed PMID: 26070531.


Hohenforst-Schmidt W, Zarogoulidis P, Stopek J, Vogl T, Hübner F, Turner JF, Browning R, Zarogoulidis K, Drevelegas A, Drevelegas K, Darwiche K, Freitag L, Rittger H. DDMC-p53 gene therapy with or without cisplatin and microwave ablation. Onco Targets Ther. 2015 May 20;8:1165-73. doi: 10.2147/OTT.S83794. eCollection 2015. PubMed PMID: 26056480; PubMed Central PMCID: PMC4446017.


Yang JC, Sequist LV, Geater SL, Tsai CM, Mok TS, Schuler M, Yamamoto N, Yu CJ, Ou SH, Zhou C, Massey D, Zazulina V, Wu YL. Clinical activity of afatinib in patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations: a combined post-hoc analysis of LUX-Lung 2, LUX-Lung 3, and LUX-Lung 6. Lancet Oncol. 2015 Jul;16(7):830-8. doi: 10.1016/S1470-2045(15)00026-1. Epub 2015 Jun 4. PubMed PMID: 26051236.


Hohenforst-Schmidt W, Linsmeier B, Zarogoulidis P, Freitag L, Darwiche K, Browning R, Turner JF, Huang H, Li Q, Vogl T, Zarogoulidis K, Brachmann J, Rittger H. Transtracheal single-point stent fixation in posttracheotomy tracheomalacia under cone-beam computer tomography guidance by transmural suturing with the Berci needle – a perspective on a new tool to avoid stent migration of Dumon stents. Ther Clin Risk Manag. 2015 May 22;11:837-50. doi: 10.2147/TCRM.S83230. eCollection 2015. PubMed PMID: 26045666; PubMed Central PMCID: PMC4448926.


Thatcher N, Hirsch FR, Luft AV, Szczesna A, Ciuleanu TE, Dediu M, Ramlau R, Galiulin RK, Bálint B, Losonczy G, Kazarnowicz A, Park K, Schumann C, Reck M, Depenbrock H, Nanda S, Kruljac-Letunic A, Kurek R, Paz-Ares L, Socinski MA. SQUIRE Investigators. Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): an open-label, randomised, controlled phase 3 trial. Lancet Oncol. 2015 Jul;16(7):763-74. doi: 10.1016/S1470-2045(15)00021-2. Epub 2015 Jun 1. PubMed PMID: 26045340.


Grignani G, Martín-Broto J, Schuler M, Reichardt P. Trabectedin clinical cases: use according to indication in diverse clinical scenarios. Future Oncol. 2015;11(11 Suppl):15-24. doi: 10.2217/fon.15.76. PubMed PMID: 26043311.


Brahmer J, Reckamp KL, Baas P, Crinò L, Eberhardt WE, Poddubskaya E, Antonia S, Pluzanski A, Vokes EE, Holgado E, Waterhouse D, Ready N, Gainor J, Arén Frontera O, Havel L, Steins M, Garassino MC, Aerts JG, Domine M, Paz-Ares L, Reck M, Baudelet C, Harbison CT, Lestini B, Spigel DR. Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer. N Engl J Med. 2015 Jul 9;373(2):123-35. doi: 10.1056/NEJMoa1504627. Epub 2015 May 31. PubMed PMID: 26028407.


Chapman KR, Burdon JG, Piitulainen E, Sandhaus RA, Seersholm N, Stocks JM, Stoel BC, Huang L, Yao Z, Edelman JM, McElvaney NG. RAPID Trial Study Group. Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial. Lancet. 2015 Jul 25;386(9991):360-8. doi: 10.1016/S0140-6736(15)60860-1. Epub 2015 May 27. PubMed PMID: 26026936.


Walter RF, Werner R, Ting S, Vollbrecht C, Theegarten D, Christoph DC, Kurt Werner S, Wohlschlaeger J, Mairinger FD. Identification of deregulation of apoptosis and cell cycle in neuroendocrine tumors of the lung via NanoString nCounter expression analysis. Oncotarget. 2015 Sep 22;6(28):24690-8. doi: 10.18632/oncotarget.3992. PubMed PMID: 26008974.


Lampaki S, Lazaridis G, Zarogoulidis K, Kioumis I, Papaiwannou A, Tsirgogianni K, Karavergou A, Tsiouda T, Karavasilis V, Yarmus L, Darwiche K, Freitag L, Sakkas A, Kantzeli A, Baka S, Hohenforst-Schmidt W, Zarogoulidis P. Defining the role of tyrosine kinase inhibitors in early stage non-small cell lung cancer. J Cancer. 2015 May 7;6(6):568-74. doi: 10.7150/jca.11893. eCollection 2015. Review. PubMed PMID: 26000049; PubMed Central PMCID: PMC4439943.


Stamatis G. Staging of lung cancer: the role of noninvasive, minimally invasive and invasive techniques. Eur Respir J. 2015 Aug;46(2):521-31. doi: 10.1183/09031936.00126714. Epub 2015 May 14. Review. PubMed PMID: 25976686.


Cheufou DH, Hager T, Welter S, Theegarten D, Stamatis G. Pulmonary manifestation of a condition resembling Kasabach-Merritt syndrome in a woman with abdominal angiomatosis associated with consumptive coagulopathy—surgical management: a case report. J Med Case Rep. 2015 May 9;9:107. doi: 10.1186/s13256-015-0566-z. PubMed PMID: 25956942; PubMed Central PMCID: PMC4436809.


Nathan SD, du Bois RM, Albera C, Bradford WZ, Costabel U, Kartashov A, Noble PW, Sahn SA, Valeyre D, Weycker D, King TE Jr. Validation of test performance characteristics and minimal clinically important difference of the 6-minute walk test in patients with idiopathic pulmonary fibrosis. Respir Med. 2015 Jul;109(7):914-22. doi: 10.1016/j.rmed.2015.04.008. Epub 2015 Apr 24. PubMed PMID: 25956020.


Pöttgen C, Stuschke M, Graupner B, Theegarten D, Gauler T, Jendrossek V, Freitag L, Jawad JA, Gkika E, Wohlschlaeger J, Welter S, Hoiczyk M, Schuler M, Stamatis G, Eberhardt W. Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factors. BMC Cancer. 2015 May 6;15:363. doi: 10.1186/s12885-015-1389-4. PubMed PMID: 25943191; PubMed Central PMCID: PMC4428235.


Pöttgen C, Abu Jawad J, Gkika E, Freitag L, Lübcke W, Welter S, Gauler T, Schuler M, Eberhardt WE, Stamatis G, Stuschke M. Accelerated radiotherapy and concurrent chemotherapy for patients with contralateral central or mediastinal lung cancer relapse after pneumonectomy. J Thorac Dis. 2015 Mar;7(3):264-72. doi: 10.3978/j.issn.2072-1439.2015.01.59. PubMed PMID: 25922702; PubMed Central PMCID: PMC4387447.


Eberhardt WE, De Ruysscher D, Weder W, Le Péchoux C, De Leyn P, Hoffmann H, Westeel V, Stahel R, Felip E, Peters S. Panel Members. 2nd ESMO Consensus Conference in Lung Cancer: locally advanced stage III non-small-cell lung cancer. Ann Oncol. 2015 Aug;26(8):1573-88. doi: 10.1093/annonc/mdv187. Epub 2015 Apr 20. PubMed PMID: 25897013.


Schuler M, Spanier K, Lukasczik M, Schwarze M, Musekamp G, Osborne RH, Faller H, Pohrt U. Individual prevention courses for occupational skin diseases: changes in and relationships between proximal and distal outcomes. Contact Dermatitis. 2015 Jun;72(6):371-80. doi: 10.1111/cod.12367. Epub 2015 Apr 5. PubMed PMID: 25845413.


Walter RF, Mairinger FD, Werner R, Ting S, Vollbrecht C, Theegarten D, Christoph DC, Zarogoulidis K, Schmid KW, Zarogoulidis P, Wohlschlaeger J. SOX4, SOX11 and PAX6 mRNA expression was identified as a (prognostic) marker for the aggressiveness of neuroendocrine tumors of the lung by using next-generation expression analysis (NanoString). Future Oncol. 2015;11(7):1027-36. doi: 10.2217/fon.15.18. PubMed PMID: 25804118.


Trautmann F, Schuler M, Schmitt J. Burden of soft-tissue and bone sarcoma in routine care: Estimation of incidence, prevalence and survival for health services research. Cancer Epidemiol. 2015 Jun;39(3):440-6. doi: 10.1016/j.canep.2015.03.002. Epub 2015 Mar 21. PubMed PMID: 25801944.


Krug LM, Kindler HL, Calvert H, Manegold C, Tsao AS, Fennell D, Öhman R, Plummer R, Eberhardt WE, Fukuoka K, Gaafar RM, Lafitte JJ, Hillerdal G, Chu Q, Buikhuisen WA, Lubiniecki GM, Sun X, Smith M, Baas P. Vorinostat in patients with advanced malignant pleural mesothelioma who have progressed on previous chemotherapy (VANTAGE-014): a phase 3, double-blind, randomised, placebo-controlled trial. Lancet Oncol. 2015 Apr;16(4):447-56. doi: 10.1016/S1470-2045(15)70056-2. Epub 2015 Mar 20. Erratum in: Lancet Oncol. 2015 May;16(5):e199. PubMed PMID: 25800891.


Welter S, Cheufou D, Darwiche K, Stamatis G. [Tracheal injuries, fistulae from bronchial stump and bronchial anastomoses and recurrent laryngeal nerve paralysis : management of complications in thoracic surgery]. Chirurg. 2015 May;86(5):410-8. doi: 10.1007/s00104-014-2862-3. German. PubMed PMID: 25794450.


Wessendorf TE, Bonella F, Costabel U. Diagnosis of Sarcoidosis. Clin Rev Allergy Immunol. 2015 Aug;49(1):54-62. doi: 10.1007/s12016-015-8475-x. PubMed PMID: 25779004.


Domvri K, Bougiouklis D, Zarogoulidis P, Porpodis K, Xristoforidis M, Liaka A, Eleutheriadou E, Lampaki S, Lazaridis G, Organtzis J, Kyriazis G, Hohenforst-Schmidt W, Tsirgogianni K, Karavasilis V, Baka S, Darwiche K, Freitag L, Trakada G, Zarogoulidis K. Could Somatostatin Enhance the Outcomes of Chemotherapeutic Treatment in SCLC? J Cancer. 2015 Feb 23;6(4):360-6. doi: 10.7150/jca.11308. eCollection 2015. PubMed PMID: 25767606; PubMed Central PMCID: PMC4349876.


Besa V, Teschler H, Kurth I, Khan AM, Zarogoulidis P, Baumbach JI, Sommerwerck U, Freitag L, Darwiche K. Exhaled volatile organic compounds discriminate patients with chronic obstructive pulmonary disease from healthy subjects. Int J Chron Obstruct Pulmon Dis. 2015 Feb 23;10:399-406. doi: 10.2147/COPD.S76212. eCollection 2015. PubMed PMID: 25759572; PubMed Central PMCID: PMC4346009.


Costabel U. The changing treatment landscape in idiopathic pulmonary fibrosis. Eur Respir Rev. 2015 Mar;24(135):65-8. doi: 10.1183/09059180.00011414. Review. PubMed PMID: 25726557.


Teschler H. Long-term experience in the treatment of α1-antitrypsin deficiency: 25 years of augmentation therapy. Eur Respir Rev. 2015 Mar;24(135):46-51. doi: 10.1183/09059180.10010714. Review. PubMed PMID: 25726554.


Reis H, Herold T, Ting S, Worm K, Huber U, Christoph DC, Eberhardt WE, Kostbade K, Kasper S, Stamatis G, Welter S, Darwiche K, Karpf-Wissel R, Theegarten D, Schmid KW, Schuler M, Wiesweg M. HER2 expression and markers of phosphoinositide-3-kinase pathway activation define a favorable subgroup of metastatic pulmonary adenocarcinomas. Lung Cancer. 2015 Apr; 88(1):34-41. doi: 10.1016/j.lungcan.2015.02.002. Epub 2015 Feb 7. PubMed PMID: 25708529.


Walter RF, Mairinger FD, Ting S, Vollbrecht C, Mairinger T, Theegarten D, Christoph DC, Schmid KW, Wohlschlaeger J. MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53. Br J Cancer. 2015 Mar 3;112(5):883-90. doi: 10.1038/bjc.2015.27. Epub 2015 Feb 10. PubMed PMID: 25668009; PubMed Central PMCID: PMC4453955.


Kampe S, Weinreich G, Darr C, Stamatis G, Hachenberg T. Controlled-Release Oxycodone as „Gold Standard“ for Postoperative Pain Therapy in Patients Undergoing Video-Assisted Thoracic Surgery or Thoracoscopy: A Retrospective Evaluation of 788 Cases. Thorac Cardiovasc Surg. 2015 Sep;63(6):510-3. doi: 10.1055/s-0034-1396682. Epub 2015 Jan 20. PubMed PMID: 25602848.


Itai J, Ohshimo S, Kida Y, Ota K, Iwasaki Y, Hirohashi N, Bonella F, Guzman J, Costabel U, Kohno N, Tanigawa K. A pilot study: a combined therapy using polymyxin-B hemoperfusion and extracorporeal membrane oxygenation for acute exacerbation of interstitial pneumonia. Sarcoidosis Vasc Diffuse Lung Dis. 2015 Jan 5;31(4):343-9. PubMed PMID: 25591146.


Yang JC, Wu YL, Schuler M, Sebastian M, Popat S, Yamamoto N, Zhou C, Hu CP, O’Byrne K, Feng J, Lu S, Huang Y, Geater SL, Lee KY, Tsai CM, Gorbunova V, Hirsh V, Bennouna J, Orlov S, Mok T, Boyer M, Su WC, Lee KH, Kato T, Massey D, Shahidi M, Zazulina V, Sequist LV. Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials. Lancet Oncol. 2015 Feb;16(2):141-51. doi: 10.1016/S1470-2045(14)71173-8. Epub 2015 Jan 12. PubMed PMID: 25589191.


Horimasu Y, Ohshimo S, Bonella F, Tanaka S, Ishikawa N, Hattori N, Kohno N, Guzman J, Costabel U. MUC5B promoter polymorphism in Japanese patients with idiopathic pulmonary fibrosis. Respirology. 2015 Apr;20(3):439-44. doi: 10.1111/resp.12466. Epub 2015 Jan 8. PubMed PMID: 25581455.


Eberhardt WE. Concurrent chemoradiotherapy in stage III non-small-cell lung cancer: what is the best regimen? J Clin Oncol. 2015 Feb 20;33(6):532-3. doi: 10.1200/JCO.2014.58.9812. Epub 2015 Jan 5. PubMed PMID: 25559800.


Andreou D, Werner M, Pink D, Traub F, Schuler M, Gosheger G, Jobke B, Reichardt P, Tunn PU. Prognostic relevance of the mitotic count and the amount of viable tumour after neoadjuvant chemotherapy for primary, localised, high-grade soft tissue sarcoma. Br J Cancer. 2015 Feb 3;112(3):455-60. doi: 10.1038/bjc.2014.635. Epub 2014 Dec 23. PubMed PMID: 25535732; PubMed Central PMCID: PMC4453655.


Bonella F, Sixt SU, Thomassen J, Schmidt M, Cai M, Mori T, Guzman J, Costabel U. Extracellular 20S proteasome in BAL and serum of patients with alveolar proteinosis. Immunobiology. 2015 Mar;220(3):382-8. doi:10.1016/j.imbio.2014.10.010. Epub 2014 Oct 23. PubMed PMID: 25534398.


Großerueschkamp F, Kallenbach-Thieltges A, Behrens T, Brüning T, Altmayer M, Stamatis G, Theegarten D, Gerwert K. Marker-free automated histopathological annotation of lung tumour subtypes by FTIR imaging. Analyst. 2015 Apr 7;140(7):2114-20. doi: 10.1039/c4an01978d. PubMed PMID: 25529256.


Freitag L, Lenkens D, Zarogoulidis P, Karpf-Wissel R, Hang H, Darwiche K. Functional bronchoscopy: development of a new bronchoscopic method for real-time gas exchange assessment of lobes and lung segments. Respiration. 2014;88(6):469-77. doi: 10.1159/000368087. Epub 2014 Nov 28. PubMed PMID: 25472469.


Wuyts WA, Antoniou KM, Borensztajn K, Costabel U, Cottin V, Crestani B, Grutters JC, Maher TM, Poletti V, Richeldi L, Vancheri C, Wells AU. Combination therapy: the future of management for idiopathic pulmonary fibrosis? Lancet Respir Med. 2014 Nov;2(11):933-42. doi: 10.1016/S2213-2600(14)70232-2. Epub 2014 Nov 3. Erratum in: Lancet Respir Med. 2015 Jan;3(1):e2. PubMed PMID: 25439569.


Weinreich G, Terjung S, Wang Y, Werther S, Zaffaroni A, Teschler H. Validation of SleepMinder as screening device for obstructive sleep apnea. Somnologie 2014;18(4):238-42.


Oezkan F, Khan AM, Freitag L, Montag M, Hahn S, Berliner PJ, Darwiche K. Hemoptysis in primary pulmonary amyloidoma treated with intrabronchial arterial coiling. Am J Respir Crit Care Med. 2014 Dec 1;190(11):1311-4. doi: 10.1164/rccm.201406-1009IM. PubMed PMID: 25436781.


Oezkan F, Khan A, Zarogoulidis P, Hohenforst-Schmidt W, Theegarten D, Yasufuku K, Nakajima T, Freitag L, Darwiche K. Efficient utilization of EBUS-TBNA samples for both diagnosis and molecular analyses. Onco Targets Ther. 2014 Nov 10;7:2061-5. doi: 10.2147/OTT.S72974. eCollection 2014. PubMed PMID: 25419143; PubMed Central PMCID: PMC4234164.


Kampe S, Weinreich G, Darr C, Eicker K, Stamatis G, Hachenberg T. The impact of epidural analgesia compared to systemic opioid-based analgesia with regard to length of hospital stay and recovery of bowel function: retrospective evaluation of 1555 patients undergoing thoracotomy. J Cardiothorac Surg. 2014 Nov 23;9:175. doi: 10.1186/s13019-014-0175-8. PubMed PMID: 25417134; PubMed Central PMCID: PMC4246432.


Zarogoulidis P, Hohenforst-Schmidt W, Huang H, Sahpatzidou D, Freitag L, Sakkas L, Rapti A, Kioumis I, Pitsiou G, Kouzi-Koliakos K, Papamichail A, Papaiwannou A, Tsiouda T, Tsakiridis K, Porpodis K, Lampaki S, Organtzis J, Gschwendtner A, Zarogoulidis K. A gene therapy induced emphysema model and the protective role of stem cells. Diagn Pathol. 2014 Nov 14;9:195. doi:10.1186/s13000-014-0195-7. PubMed PMID: 25394479; PubMed Central PMCID: PMC4243373.


Huang H, Zarogoulidis P, Lampaki S, Organtzis J, Petridis D, Porpodis K, Papaiwannou A, Karageorgiou V, Pitsiou G, Kioumis I, Hohenforst-Schmidt W, Li Q, Darwiche K, Freitag L, Rapti A, Zarogoulidis K. Experimentation with aerosol bonsetan, pirfenidone, treprostinil and sidenafil. J Thorac Dis. 2014 Oct;6(10):1411-9. doi: 10.3978/j.issn.2072-1439.2014.08.38. PubMed PMID: 25364518; PubMed Central PMCID: PMC4215150.


Costabel U, Albera C, Bradford WZ, Hormel P, King TE Jr, Noble PW, Sahn SA, Valeyre D, Du Bois RM. Analysis of lung function and survival in RECAP: An open-label extension study of pirfenidone in patients with idiopathic pulmonary fibrosis. Sarcoidosis Vasc Diffuse Lung Dis. 2014 Oct 20;31(3):198-205. PubMed PMID: 25363219.


Sixt SU, Costabel U, Bonella F, Grunert K, Alami R, Hakenbeck J, Bauer P, Dahlmann B, Schmid KW, Peters J, Wohlschlaeger J. Alveolar and intraparenchymal proteasome in sarcoidosis. Respir Med. 2014 Oct;108(10):1534-41. doi: 10.1016/j.rmed.2014.09.004. Epub 2014 Sep 19. PubMed PMID: 25269709.


Schuler M, Fischer JR, Grohé C, Gütz S, Thomas M, Kimmich M, Schneider CP, Laack E, Märten A. Afatinib Compassionate Use Consortium. Experience with afatinib in patients with non-small cell lung cancer progressing after clinical benefit from gefitinib and erlotinib. Oncologist. 2014 Oct;19(10):1100-9. doi: 10.1634/theoncologist.2014-0103. Epub 2014 Sep 17. PubMed PMID: 25232040; PubMed Central PMCID: PMC4200993.


Kampe, S, Lüttecke, D, Wolter, K, Cheufou, DH, Stamatis G. Minimal incidence of chronic and neuropathic postthoracotomy pain after anteroaxillary thoracotomy with consequent systemic pain therapy. Sept 2014, Eur J Anaesthesiol.


Deppermann KM, Hoffmann H, Eberhardt WE. Benefits and risks of lung cancer screening. Oncol Res Treat. 2014;37 Suppl 3:58-66. doi: 10.1159/000365234. Epub 2014 Aug 29. PubMed PMID: 25195833.


Mairinger FD, Walter RF, Theegarten D, Hager T, Vollbrecht C, Christoph DC, Worm K, Ting S, Werner R, Stamatis G, Mairinger T, Baba H, Zarogoulidis K, Huang H, Li Q, Tsakiridis K, Zarogoulidis P, Schmid KW, Wohlschlaeger J. Gene Expression Analysis of the 26S Proteasome Subunit PSMB4 Reveals Significant Upregulation, Different Expression and Association with Proliferation in Human Pulmonary Neuroendocrine Tumours. J Cancer. 2014 Aug 1;5(8):646-54. doi: 10.7150/jca.9955. eCollection 2014. PubMed PMID: 25157275; PubMed Central PMCID: PMC4142326.


Organtzis J, Lampaki S, Zarogoulidis P, Huang H, Li Q, Papaiwannou A, Syrigos K, Porpodis K, Tsiouda T, Hohenforst-Schmidt W, Trakada G, Walter RF, Makrantonaki D, Pitsiou G, Kioumis I, Zarogoulidis K. DAXAS and COPD Correlation with Cancer. J Cancer. 2014 Aug 1;5(8):625-7. doi: 10.7150/jca.9730. eCollection 2014. PubMed PMID: 25157272; PubMed Central PMCID: PMC4142323.


Mairinger FD, Walter RF, Vollbrecht C, Hager T, Worm K, Ting S, Wohlschläger J, Zarogoulidis P, Zarogoulidis K, Schmid KW. Isothermal multiple displacement amplification: a methodical approach enhancing molecular routine diagnostics of microcarcinomas and small biopsies. Onco Targets Ther. 2014 Aug 13;7:1441-7. doi: 10.2147/OTT.S65144. eCollection 2014. PubMed PMID: 25152625; PubMed Central PMCID: PMC4140239.


Cheufou DH, Welter S, Chalvatzoulis E, Christof D, Theegarten D, Stamatis G. Surgery of primary lung cancer with oligometastatic m1b synchronous single brain metastasis: analysis of 37 cases. Thorac Cardiovasc Surg. 2014 Oct;62(7):612-5. doi: 10.1055/s-0034-1377060. Epub 2014 Aug 19. PubMed PMID: 25136943.


Welter S, Cheufou D, Zahin M, Kampe S, Darwiche K, Weinreich G, Stamatis G. Short- and Mid-Term Changes in Lung Function after Bilateral Pulmonary Metastasectomy. Thorac Cardiovasc Surg. 2014 Jul 28. [Epub ahead of print] PubMed PMID: 25068776.


Stamatis G. Neuroendocrine tumors of the lung: the role of surgery in small cell lung cancer. Thorac Surg Clin. 2014 Aug;24(3):313-26. doi: 10.1016/j.thorsurg.2014.05.004. Review. PubMed PMID: 25065933.


Flaherty KR, Fell C, Aubry MC, Brown K, Colby T, Costabel U, Franks TJ, Gross BH, Hansell DM, Kazerooni E, Kim DS, King TE Jr, Kitachi M, Lynch D, Myers J,Nagai S, Nicholson AG, Poletti V, Raghu G, Selman M, Toews G, Travis W, Wells AU,Vassallo R, Martinez FJ. Smoking-related idiopathic interstitial pneumonia. Eur Respir J. 2014 Sep;44(3):594-602. doi: 10.1183/09031936.00166813. Epub 2014 Jul 25. PubMed PMID: 25063244; PubMed Central PMCID: PMC4366053.


Schmidt LH, Görlich D, Spieker T, Rohde C, Schuler M, Mohr M, Humberg J, Sauer T, Thoenissen NH, Huge A, Voss R, Marra A, Faldum A, Müller-Tidow C, Berdel WE, Wiewrodt R. Prognostic impact of Bcl-2 depends on tumor histology and expression of MALAT-1 lncRNA in non-small-cell lung cancer. J Thorac Oncol. 2014 Sep;9(9):1294-304. doi: 10.1097/JTO.0000000000000243. PubMed PMID: 25036876.


Judson MA, Baughman RP, Costabel U, Drent M, Gibson KF, Raghu G, Shigemitsu H, Barney JB, Culver DA, Hamzeh NY, Wijsenbeek MS, Albera C, Huizar I, Agarwal P, Brodmerkel C, Watt R, Barnathan ES. Safety and efficacy of ustekinumab or golimumab in patients with chronic sarcoidosis. Eur Respir J. 2014 Nov;44(5):1296-307. doi: 10.1183/09031936.00000914. Epub 2014 Jul 17. PubMed PMID: 25034562.


Darwiche K, Özkan F, Ting S, Johnen G, Brüning T, Soltermann A, Huber LC, Christoph DC, Freitag L, Franzen D. [Role of pretherapeutic biomarkers in lung cancer with special regards to bronchoscopic procedures]. Pneumologie. 2014 Nov;68(11):719-26. doi: 10.1055/s-0034-1377299. Epub 2014 Jul 8. Review. German. PubMed PMID: 25003906.


Christoph DC, Reyna-Asuncion B, Hassan B, Tran C, Maltzman JD, O’Shannessy DJ, Gauler TC, Wohlschlaeger J, Schuler M, Eberhardt WE, Hirsch FR. Assessment of folate receptor-α and epidermal growth factor receptor expression in pemetrexed-treated non-small-cell lung cancer patients. Clin Lung Cancer. 2014 Sep;15(5):320-30.e1-3. doi: 10.1016/j.cllc.2014.05.002. Epub 2014 Jun 3. PubMed PMID: 24993594.


Mairinger FD, Walter RF, Werner R, Christoph DC, Ting S, Vollbrecht C, Zarogoulidis K, Huang H, Li Q, Schmid KW, Wohlschlaeger J, Zarogoulidis P. Activation of angiogenesis differs strongly between pulmonary carcinoids and neuroendocrine carinomas and is crucial for carcinoid tumourgenesis. J Cancer. 2014 May 15;5(6):465-71. doi: 10.7150/jca.9235. eCollection 2014. PubMed PMID: 24959299; PubMed Central PMCID: PMC4066358.


Mairinger FD, Walter RF, Ting S, Vollbrecht C, Kollmeier J, Griff S, Hager T, Mairinger T, Christoph DC, Theegarten D, Schmid KW, Wohlschlaeger J. Mdm2 protein expression is strongly associated with survival in malignant pleural mesothelioma. Future Oncol. 2014 May;10(6):995-1005. doi: 10.2217/fon.13.261. PubMed PMID: 24941985.


Roesel C, Welter S, Stamatis G, Theegarten D, Tappe D. Management of a chest-wall soft-tissue tumor caused by an infection with the larval tapeworm pathogen Taenia crassiceps. Am J Trop Med Hyg. 2014 Sep;91(3):541-3. doi: 10.4269/ajtmh.14-0185. Epub 2014 Jun 9. PubMed PMID: 24914004; PubMed Central PMCID: PMC4155556.


Mairinger FD, Ting S, Werner R, Walter RF, Hager T, Vollbrecht C, Christoph D, Worm K, Mairinger T, Sheu-Grabellus SY, Theegarten D, Schmid KW, Wohlschlaeger J. Different micro-RNA expression profiles distinguish subtypes of neuroendocrine tumors of the lung: results of a profiling study. Mod Pathol. 2014 Dec;27(12):1632-40. doi: 10.1038/modpathol.2014.74. Epub 2014 May 30. PubMed PMID: 24875640.


Werther S, Teschler H. [Sleep medicine: new data]. Dtsch Med Wochenschr. 2014 Jun;139(23):1231-3. doi: 10.1055/s-0034-1370061. Epub 2014 May 27. Review. German. PubMed PMID: 24866956.


Valeyre D, Albera C, Bradford WZ, Costabel U, King TE Jr, Leff JA, Noble PW, Sahn SA, du Bois RM. Comprehensive assessment of the long-term safety of pirfenidone in patients with idiopathic pulmonary fibrosis. Respirology. 2014 Jul;19(5):740-7. doi: 10.1111/resp.12297. Epub 2014 May 18. PubMed PMID: 24836849; PubMed Central PMCID: PMC4230393.


Richeldi L, du Bois RM, Raghu G, Azuma A, Brown KK, Costabel U, Cottin V, Flaherty KR, Hansell DM, Inoue Y, Kim DS, Kolb M, Nicholson AG, Noble PW, Selman M, Taniguchi H, Brun M, Le Maulf F, Girard M, Stowasser S, Schlenker-Herceg R, Disse B, Collard HR. INPULSIS Trial Investigators. Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis. N Engl J Med. 2014 May 29;370(22):2071-82. doi: 10.1056/NEJMoa1402584. Epub 2014 May 18. Erratum in: N Engl J Med. 2015 Aug 20;373(8):782. PubMed PMID: 24836310.


Ohshimo S, Ishikawa N, Horimasu Y, Hattori N, Hirohashi N, Tanigawa K, Kohno N, Bonella F, Guzman J, Costabel U. Baseline KL-6 predicts increased risk for acute exacerbation of idiopathic pulmonary fibrosis. Respir Med. 2014 Jul;108(7):1031-9. doi: 10.1016/j.rmed.2014.04.009. Epub 2014 Apr 26. PubMed PMID: 24835074.


Delcey MG, Freitag L, Pedersen TB, Aquilante F, Lindh R, González L. Analytical gradients of complete active space self-consistent field energies using Cholesky decomposition: geometry optimization and spin-state energetics of a ruthenium nitrosyl complex. J Chem Phys. 2014 May 7;140(17):174103. doi: 10.1063/1.4873349. PubMed PMID: 24811621.


Nensa F, Stattaus J, Morgan B, Horsfield MA, Soria JC, Besse B, Gounant V, Khalil A, Seng K, Fischer B, Krissel H, Laurent D, Christoph D, Eberhardt WE, Gauler TC. Dynamic contrast-enhanced MRI parameters as biomarkers for the effect of vatalanib in patients with non-small-cell lung cancer. Future Oncol. 2014 Apr;10(5):823-33. doi: 10.2217/fon.13.248. PubMed PMID: 24799063.


Valipour A, Slebos DJ, de Oliveira HG, Eberhardt R, Freitag L, Criner GJ, Herth FJ. Expert statement: pneumothorax associated with endoscopic valve therapy for emphysema–potential mechanisms, treatment algorithm, and case examples. Respiration. 2014;87(6):513-21. doi: 10.1159/000360642. Epub 2014 Apr 24. PubMed PMID: 24777292.


Judson MA, Costabel U, Drent M, Wells A, Maier L, Koth L, Shigemitsu H, Culver DA, Gelfand J, Valeyre D, Sweiss N, Crouser E, Morgenthau AS, Lower EE, Azuma A, Ishihara M, Morimoto S, Tetsuo Yamaguchi T, Shijubo N, Grutters JC, Rosenbach M, Li HP, Rottoli P, Inoue Y, Prasse A, Baughman RP. Organ Assessment Instrument Investigators TW. The WASOG Sarcoidosis Organ Assessment Instrument: An update of a previous clinical tool. Sarcoidosis Vasc Diffuse Lung Dis. 2014 Apr 18;31(1):19-27. PubMed PMID: 24751450.


Woehrle H, Oldenburg O, Arzt M, Graml A, Erdmann E, Teschler H, Wegscheider K. SCHLA-HF Investigators. Determining the prevalence and predictors of sleep disordered breathing in patients with chronic heart failure: rationale and design of the SCHLA-HF registry. BMC Cardiovasc Disord. 2014 Apr 9;14:46. doi: 10.1186/1471-2261-14-46. PubMed PMID: 24716484; PubMed Central PMCID: PMC3983862.


Hohenforst-Schmidt W, Zarogoulidis P, Oezkan F, Mahnkopf C, Grabenbauer G, Kreczy A, Bartunek R, Darwiche K, Freitag L, Li Q, Huang H, Vogl T, Lepilvert P, Tsiouda T, Tsakiridis K, Zarogoulidis K, Brachmann J. „Denervation“ of autonomous nervous system in idiopathic pulmonary arterial hypertension by low-dose radiation: a case report with an unexpected outcome. Ther Clin Risk Manag. 2014 Mar 27;10:207-15. doi: 10.2147/TCRM.S58705. eCollection 2014. PubMed PMID: 24707181; PubMed Central PMCID: PMC3972028.


Shaw AT, Kim DW, Mehra R, Tan DS, Felip E, Chow LQ, Camidge DR, Vansteenkiste J, Sharma S, De Pas T, Riely GJ, Solomon BJ, Wolf J, Thomas M, Schuler M, Liu G, Santoro A, Lau YY, Goldwasser M, Boral AL, Engelman JA. Ceritinib in ALK-rearranged non-small-cell lung cancer. N Engl J Med. 2014 Mar 27;370(13):1189-97. doi: 10.1056/NEJMoa1311107. PubMed PMID: 24670165; PubMed Central PMCID: PMC4079055.


Bonella F, Costabel U. Biomarkers in connective tissue disease-associated interstitial lung disease. Semin Respir Crit Care Med. 2014 Apr;35(2):181-200. doi: 10.1055/s-0034-1371527. Epub 2014 Mar 25. Review. PubMed PMID: 24668534.


Hohenforst-Schmidt W, Zarogoulidis P, Vogl T, Turner JF, Browning R, Linsmeier B, Huang H, Li Q, Darwiche K, Freitag L, Simoff M, Kioumis I, Zarogoulidis K, Brachmann J. Cone Beam Computertomography (CBCT) in Interventional Chest Medicine – High Feasibility for Endobronchial Realtime Navigation. J Cancer. 2014 Mar 9;5(3):231-41. doi: 10.7150/jca.8834. eCollection 2014. PubMed PMID: 24665347; PubMed Central PMCID: PMC3963080.


Dlugaj M, Weinreich G, Weimar C, Stang A, Dragano N, Wessendorf TE, Teschler H, Winkler A, Wege N, Moebus S, Möhlenkamp S, Erbel R, Jöckel KH. Heinz Nixdorf Recall Study Investigative Group. Sleep-disordered breathing, sleep quality, and mild cognitive impairment in the general population. J Alzheimers Dis. 2014;41(2):479-97. doi: 10.3233/JAD-132132. PubMed PMID: 24643134.


Costabel U, Bendstrup E, Cottin V, Dewint P, Egan JJ, Ferguson J, Groves R, Hellström PM, Kreuter M, Maher TM, Molina-Molina M, Nordlind K, Sarafidis A, Vancheri C. Pirfenidone in idiopathic pulmonary fibrosis: expert panel discussion on the management of drug-related adverse events. Adv Ther. 2014 Apr;31(4):375-91. doi: 10.1007/s12325-014-0112-1. Epub 2014 Mar 18. Erratum in: Adv Ther. 2014 May;31(5):575-6. PubMed PMID: 24639005; PubMed Central PMCID: PMC4003341.


Funke F, Gauler T, Freitag L, Pöttgen C. Using endobronchial valves to reduce irradiation portals in lung cancer: a case report. Pract Radiat Oncol. 2014 Jan-Feb;4(1):e91-4. doi: 10.1016/j.prro.2013.03.002. Epub 2013 May 15. PubMed PMID: 24621438.


Walter RF, Zarogoulidis P, Mairinger FD, Werner R, Darwiche K, Zarogoulidis K, Freitag L. Cell viability of fibroblasts to pifenidone and sirolimus: a future concept for drug eluting stents. Int J Pharm. 2014 May 15;466(1-2):38-43. doi: 10.1016/j.ijpharm.2014.03.003. Epub 2014 Mar 5. PubMed PMID: 24607204.


Wirtz H, Kropp R, Behr J, Costabel U, Bonnet R, Schönfeld N, Prasse A, Kardos P, Seehausen V, Loddenkemper R. [50 years WATL (Scientific Working Group for the Therapy of Lung Diseases)]. Pneumologie. 2014 Mar;68(3):199-205. doi: 10.1055/s-0034-1365237. Epub 2014 Mar 4. Review. German. PubMed PMID: 24595854.


Antoniou KM, Margaritopoulos GA, Tomassetti S, Bonella F, Costabel U, Poletti V. Interstitial lung disease. Eur Respir Rev. 2014 Mar 1;23(131):40-54. doi: 10.1183/09059180.00009113. Review. PubMed PMID: 24591661.


Hohenforst-Schmidt W, Banckwitz R, Zarogoulidis P, Vogl T, Darwiche K, Goldberg E, Huang H, Simoff M, Li Q, Browning R, Freitag L, Turner JF, Pivert PL, Yarmus L, Zarogoulidis K, Brachmann J. Radiation Exposure of Patients by Cone Beam CT during Endobronchial Navigation – A Phantom Study. J Cancer. 2014 Feb 6;5(3):192-202. doi: 10.7150/jca.8395. eCollection 2014. PubMed PMID: 24563674; PubMed Central PMCID: PMC3931267.


Heusch P, Buchbender C, Köhler J, Nensa F, Gauler T, Gomez B, Reis H, Stamatis G, Kühl H, Hartung V, Heusner TA. Thoracic staging in lung cancer: prospective comparison of 18F-FDG PET/MR imaging and 18F-FDG PET/CT. J Nucl Med. 2014 Mar;55(3):373-8. doi: 10.2967/jnumed.113.129825. Epub 2014 Feb 6. PubMed PMID: 24504054.


Costabel U, Skowasch D, Pabst S, Störk S, Tschöpe C, Allewelt M, Worth H, Müller-Quernheim J, Grohé C. [Cardiac sarcoidosis: diagnostic and therapeutic algorithms]. Pneumologie. 2014 Feb;68(2):124-32. doi: 10.1055/s-0033-1359197. Epub 2014 Feb 4. German. PubMed PMID: 24497049.


Oldenburg O, Teschler H. [Heart and lung]. Herz. 2014 Feb;39(1):7. doi: 10.1007/s00059-014-4061-x. German. PubMed PMID: 24496669.


Sommerwerck U, Rabis T, Fleimisch P, Carstens H, Teschler H, Kamler M. [Lung transplantation]. Herz. 2014 Feb;39(1):74-83. doi: 10.1007/s00059-013-4044-3. German. PubMed PMID: 24477632.


King TE Jr, Albera C, Bradford WZ, Costabel U, du Bois RM, Leff JA, Nathan SD, Sahn SA, Valeyre D, Noble PW. All-cause mortality rate in patients with idiopathic pulmonary fibrosis. Implications for the design and execution of clinical trials. Am J Respir Crit Care Med. 2014 Apr 1;189(7):825-31. doi: 10.1164/rccm.201311-1951OC. PubMed PMID: 24476390.


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Möhlenkamp S, Weinreich G, Neumann T, Voshaar T, Teschler H. [Medical therapy of heart and lung diseases. Effects on the respective other organ]. Herz. 2014 Feb;39(1):15-24. doi: 10.1007/s00059-013-4035-4. German. PubMed PMID: 24452761.


Fistera D, Steveling H, Koch A, Teschler H. [Cardiac surgery in underlying chronic pulmonary disease. Prognostic implications and efficient preoperative evaluation]. Herz. 2014 Feb;39(1):45-52. doi: 10.1007/s00059-013-4034-5. German. PubMed PMID: 24452760.


van Oorschot B, Assenbrunner B, Schuler M, Beckmann G, Flentje M. Survival and prognostic factors after moderately hypofractionated palliative thoracic radiotherapy for non-small cell lung cancer. Strahlenther Onkol. 2014 Mar;190(3):270-5. doi: 10.1007/s00066-013-0507-y. Epub 2014 Jan 12. PubMed PMID: 24413894.


Horimasu Y, Hattori N, Ishikawa N, Tanaka S, Bonella F, Ohshimo S, Guzman J, Costabel U, Kohno N. Differences in serum SP-D levels between German and Japanesesubjects are associated with SFTPD gene polymorphisms. BMC Med Genet. 2014 Jan 8;15:4. doi: 10.1186/1471-2350-15-4. PubMed PMID: 24400879; PubMed Central PMCID: PMC3893448.